Antiinflammatory Effect of Peripheral Nerve Blockade

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Antiinflammatory effect of peripheral nerve blockade.

To the Editor:—We read with interest Martin et al.’s study on the antiinflammatory effect of peripheral nerve block after total knee arthroplasty. We would be delighted to see such an outcome; however, we wish to raise the following questions on the conclusion drawn that peripheral nerve blocks have a clinical antiinflammatory effect, especially when there was no change in inflammatory mediator...

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Peripheral Nerve Blockade

1Department of Anaesthesiology and Intensive Care Medicine, Semmelweis University, Kutvolgyi ut 4, 1125 Budapest, Hungary 2Department of Anaesthesia and Intensive Care Medicine, Lapeyronie Hospital, Montpellier, France 3Department of Anesthesiology and Pain Medicine, Western Memorial Regional Hospital, 1 Brookfield Avenue, Corner Brook, NL, Canada A2H 6J7 4Department of Anaesthesia and Intensiv...

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Antiinflammatory effect of peripheral nerve blocks after knee surgery: clinical and biologic evaluation.

BACKGROUND Nerve blocks provide analgesia after surgery. The authors tested whether nerve blocks have antiinflammatory effects. METHODS Patients had combined sciatic (single-shot) and continuous femoral block (48 h) (block group) or morphine patient-controlled analgesia after total knee arthroplasty. Pain at rest and upon movement was monitored at 1 (D1), 4 (D4), and 7 days (D7) and 1 (M1) an...

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C-fiber-Selective Peripheral Nerve Blockade

Despite the clinical demand, current uses of local anesthetics do not allow selective blockade of nociceptive fibers. Regional anesthesia produces an analgesic effect accompanied with undesired side effects due to block of motor, non-nociceptive sensory and autonomic fibers. These side effects limit the clinical use of local anesthetics and affect the recovery and rehabilitation period after su...

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ژورنال

عنوان ژورنال: Anesthesiology

سال: 2009

ISSN: 0003-3022

DOI: 10.1097/aln.0b013e31819faa89